Cipro (Ciloxan, Ciprofloxacin)

Cipro Review

Ciprofloxacin is used to treat infections of the skin, lungs, airways, bones, and joints, caused by susceptible bacteria. Ciprofloxacin is also frequently used to treat urinary infections, caused by bacteria such as E. coli. Ciprofloxacin is effective in treating infectious diarrheas, caused by E. coli, campylobacter jejuni, and shigella bacteria.

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Cipro Drug Class and Mechanism

Many common infections in humans are caused by single cell organisms, called bacteria. Bacteria can grow and multiply, infecting different parts of the body. Medicines that control and eradicate these bacteria are called antibiotics. Ciprofloxacin is an antibiotic that stops multiplication of bacteria by inhibiting the reproduction and repair of their genetic material (DNA).

Cipro Uses

Ciprofloxacin may be taken with or without food. Ciprofloxacin is partially metabolized by the liver and excreted by the kidney. Dosages require adjustment in patients with severely abnormal liver or kidney function. Antacids block the absorption of ciprofloxacin and they should not be taken together. Ciprofloxacin is available in oral tablets (250, 500, 750, and 1000 mg), as well as ready-made infusion bottles (200 and 400 mg). A combination preparation of ciprofloxacin 500 mg and tinidazole 600 mg is marketed under the name Ciplox-TZ for infections where anaerobes or protozoa together with ciprofloxacin-sensitive aerobes are likely. Due to its elimination half-life, ciprofloxacin is administered twice daily. No dose adjustments are generally required for mild to moderate renal impairment.

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Cipro Side Effects

In 2005 the FDA changed the package insert for Cipro to acknowledge the tendon ruptures and the development of irreversible neurological conditions. The incidence of side effects for ciprofloxacin is acceptable and relatively safe. Approximately 9% of patients taking the medication experience side effects ranging from mild to moderate, with the vast majority of those relating to metabolic-nutritional problems and the central nervous system.Compared to other Fluoroquinolones the incidence and severity of side effects from ciprofloxacin is low.

Cipro Pregnancy

Ciprofloxacin should be avoided in pregnancy, as safe use in pregnant women has not been established.

Cipro Overdose

Canadian residents should call their local poison control center directly. Symptoms of overdose may include a change in the amount of urine.

Cipro More Information

If you experience any of the following serious side effects, stop taking ciprofloxacin and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); seizures; confusion or hallucinations; liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or muscle or joint pain; skin rash; or chest pain, chest discomfort, shortness of breath, or swelling of the legs or feet. If you experience any of the following less serious side effects, continue taking ciprofloxacin and talk to your doctor: nausea, vomiting, diarrhea; headache; dizziness or lightheadedness; drowsiness; insomnia; ringing in the ears; or increased sensitivity of the skin to sunlight. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.